Interests
- stability and flexibility of DNA double-helix
- conformational changes of molecules in solution
- nuclear magnetic resonance (NMR)
- structural changes in solid state (MAS NMR of aluminium oxides and polymers)
Teaching and thesis supervision
Curriculum vitae
2023–
Assistant Professor at the Department of Low-Temperature Physics, Faculty of Mathematics and Physics, Charles University, Prague
2020–2022
Postdoc, ETH Zurich, Solid-State NMR Group (prof. Beat H. Meier)
2009–2020
Scientist at the Department of Low-Temperature Physics, Faculty of Mathematics and Physics, Charles University, Prague
2009–2018
Ph.D. in Biophysics, chemical and macromolecular physics
Faculty of Mathematics and Physics
Doctoral thesis: “NMR study of oligonucleotide structures”
supervisor: prof. RNDr. Helena Štěpánková, CSc.
2011–2012
Teacher of Physics, Grammar school of Johannes Kepler, Prague
2007–2009
Mgr. in Biophysics and chemical physics,
Faculty of Mathematics and Physics,
thesis “NMR study of local structural stability in DNA molecule”
supervisor: prof. RNDr. Helena Štěpánková, CSc.
2004–2007
Bc. in General physics,
Faculty of Mathematics and Physics,
thesis “Monitoring of DNA duplex melting by NMR”
supervisor: prof. RNDr. Helena Štěpánková, CSc.
2000–2004
Grammar school of Johannes Kepler, Prague
List of publications
- Nguyen Minh-Ha, Palfy Gyula, Fogeron Marie-Laure, Ninot Pedrosa Marti, Zehnder Johannes, Rimal Vaclav, Callon Morgane, Lecoq Lauriane, Barnes Alexander, Meier Beat H., Böckmann Anja; Analysis of the structure and interactions of the SARS-CoV-2 ORF7b accessory protein; Proceedings of the National Academy of Sciences 121(46); 2024; 2017; doi: 10.1073/pnas.2407731121
- Římal Václav, Bunyatova Eleonora I, Štěpánková Helena; Efficient Scavenging of TEMPOL Radical by Ascorbic Acid in Solution and Related Prolongation of 13C and 1H Nuclear Spin Relaxation Times of the Solute; Molecules 29(3); 2024; 738; doi: 10.3390/molecules29030738
- Callon Morgane, Luder Dominique, Malär Alexander A., Wiegand Thomas, Římal Václav, Lecoq Lauriane, Böckmann Anja, Samoson Ago, Meier Beat H.; High and fast: NMR protein–proton side-chain assignments at 160 kHz and 1.2 GHz; Chemical Science 14(39); 2023; 10824––10834; doi: 10.1039/D3SC03539E
- Římal Václav, Callon Morgane, Malär Alexander A., Cadalbert Riccardo, Torosyan Anahit, Wiegand Thomas, Ernst Matthias, Böckmann Anja, Meier Beat H.; Correction of field instabilities in biomolecular solid-state NMR by simultaneous acquisition of a frequency reference; Magnetic Resonance 3(1); 2022; 15–26; doi: 10.5194/mr-3-15-2022
- Callon Morgane, Malär Alexander A., Pfister Sara, Římal Václav, Weber Marco E., Wiegand Thomas, Zehnder Johannes, Chávez Matías, Cadalbert Riccardo, Deb Rajdeep, Däpp Alexander, Fogeron Marie-Laure, Hunkeler Andreas, Lecoq Lauriane, Torosyan Anahit, Zyla Dawid, Glockshuber Rudolf, Jonas Stefanie, Nassal Michael, Ernst Matthias, Böckmann Anja, Meier Beat H.; Biomolecular solid-state NMR spectroscopy at 1200 MHz: the gain in resolution; Journal of Biomolecular NMR 75(6-7); 2021; 255–272; doi: 10.1007/s10858-021-00373-x
- Laguta V., Buryi M., Pejchal J., Uličná K., Římal V., Chlan V., Štěpánková H., Zagorodniy Yu, Nikl M.; Incorporation of the Ce3+ activator ions in LaAlO3 crystals: EPR and NMR study; Journal of Solid State Chemistry 313(June); 2022; 123295; doi: 10.1016/j.jssc.2022.123295
- Zoul D., Koplová M., Zimina M., Libera O., Rosnecký V., Košťál M., Šimon J., Schulc M., Vinš M., Cabalka M., Kučera J., Strunga V., Štěpánková H., Římal V., Čížek J., Štěpánek J., Procházka M.; Study of chemical processes in irradiated polycarbonate in the context of its applicability for integrating dosimetry of high doses; Radiation Physics and Chemistry 177(July); 2020; 109203; doi: 10.1016/j.radphyschem.2020.109203
- Hanzlíček Tomáš, Perná Ivana, Uličná Kateřina, Římal Václav, Štěpánková Helena; The Evaluation of Clay Suitability for Geopolymer Technology; Minerals 10(10); 2020; 852; doi: 10.3390/min10100852
- Tesar Tomas, Musalek Radek, Lukac Frantisek, Medricky Jan, Cizek Jan, Rimal Vaclav, Joshi Shrikant, Chraska Tomas; Increasing α-phase content of alumina-chromia coatings deposited by suspension plasma spraying using hybrid and intermixed concepts; Surface and Coatings Technology 371; 2019; 298–311; doi: 10.1016/j.surfcoat.2019.04.091
- Tesar Tomas, Musalek Radek, Medricky Jan, Kotlan Jiri, Lukac Frantisek, Pala Zdenek, Ctibor Pavel, Chraska Tomas, Houdkova Sarka, Rimal Vaclav, Curry Nicholas; Development of suspension plasma sprayed alumina coatings with high enthalpy plasma torch; Surface and Coatings Technology 325; 2017; 277–288; doi: 10.1016/j.surfcoat.2017.06.039
- Kozic Ján, Novák Zdeněk, Římal Václav, Profant Václav, Kuneš Jiří, Vinšová Jarmila; Conformations, equilibrium thermodynamics and rotational barriers of secondary thiobenzanilides; Tetrahedron 72(17); 2016; 2072–2083; doi: 10.1016/j.tet.2016.02.035
- Mudroňová Kateřina, Římal Václav, Mojzeš Peter; Effect of ribose versus 2′-deoxyribose residue in guanosine 5′-monophosphates on formation of G-quartets stabilized by potassium and sodium cations; Vibrational Spectroscopy 82; 2016; 60–65; doi: 10.1016/j.vibspec.2015.12.002
- Římal Václav, Socha Ondřej, Štěpánek Josef, Štěpánková Helena; Spectroscopic Study of Cytosine Methylation Effect on Thermodynamics of DNA Duplex Containing CpG Motif; JOURNAL OF SPECTROSCOPY 2015; 2015; Article ID 842810; doi: 10.1155/2015/842810
- Uličná Kateřina, Štěpánková Helena, Římal Václav, Hanzlíček Tomáš, Perná Ivana; NMR study of aluminium coordination in clays; WDS 13 PROCEEDINGS OF CONTRIBUTED PAPERS PART III; 2013;
- Římal Václav, Štěpánková Helena, Štěpánek Josef; Analysis of NMR Spectra in Case of Temperature-Dependent Chemical Exchange Between Two Unequally Populated Sites; CONCEPTS IN MAGNETIC RESONANCE PART A 38A(3); 2011; 117–127; doi: 10.1002/cmr.a.20214
- Sedláčková Eva, Římal Václav, Štěpánková Helena, Štěpánek Josef; NMR Investigation of Magnesium Specific Binding to DNA Duplex; AIP CONFERENCE PROCEEDINGS 1204; 2010; 236–238; doi: 10.1063/1.3295660