Zpět

doc. RNDr. Jan Lang, Ph.D.

Tel.: 22191 2889, 22191 2602, 22191 2603
E-mail.: jan.lang@mff.cuni.cz

Odkaz na fakultní stránku



Odborné zájmy

  • spektroskopie nukleární magnetické rezonance a zejména její aplikace založené na relaxaci jaderného spinu
  • struktura a dynamika organických supramolekulárních systémů a jejich součástí, zejména na bázi kalixarenu a kryptofanu
  • dynamika systémů vodíkových vazeb
  • využití NMR spektroskopie pro měření translační difúze tekutin v homogenním i porézním prostředí
  • dynamika biologických makromolekul

 

Odborný životopis

1989 – 1994

Magisterské studium na MFF UK v Praze, obor Fyzika, studijní směr: Fyzika molekulárních a biologických systémů

1994 – 1999

Doktorské studium na MFF UK v Praze, obor Fyzika molekulárních a biologických struktur (disertační práce: NMR study of structure and dynamics of partially rigid organic molecules, školitel: Prof. RNDr. Josef Štěpánek, CSc.).

1997 – 2011

asistent/vědecký pracovník na MFF UK - KFNT

1996 – 2006

odborný/vědecký pracovník na VŠCHT v Praze

2011

habilitace v oboru Fyzika, zaměření Fyzika molekulárních a biologických struktur

od 2011

docent na MFF UK - KFNT  

Stáže v zahraničí

1993 – 1994

roční studijní pobyt na Kat. fyzikální, anorganické a strukturní chemie Stockholmské univerzity (Prof. J. Kowalewski).

2000

půlroční studijní pobyt na Kat. fyzikální anorganické a strukturní chemie Stockholmské univerzity (Prof. J. Kowalewski).

od 2000

několik kratších pobytů (1 – 4 týdny) na Kat. materiálů a environmentální chemie (původní název Kat. fyzikální anorganické a strukturní chemie) Stockholmské univerzity (Prof. J. Kowalewski).


Seznam publikací

  1. Dvořák Petr, Šoltésová Mária, Lang Jan; Microfriction correction factor to the Stokes–Einstein equation for small molecules determined by NMR diffusion measurements and hydrodynamic modelling; Molecular Physics 117(7-8); 2019; 868-876; doi: 10.1080/00268976.2018.1510144
  2. Brezina Vaclav, Ishihara Shinsuke, Lang Jan, Hanykova Lenka, Ariga Katsuhiko, Hill Jonathan P., Labuta Jan; Structural Modulation of Chromic Response: Effects of Binding-Site Blocking in a Conjugated Calix[4]pyrrole Chromophore; ChemistryOpen 7(5); 2018; 323-335; doi: 10.1002/open.201800005
  3. Vana Jiri, Lang Jan, Soltesova Maria, Hanusek Jiri, Ruzicka Ales, Sedlak Milos, Roithova Jana; The role of trinuclear species in a palladium acetate/trifluoroacetic acid catalytic system; DALTON TRANSACTIONS 46(46); 2017; 16269-16275; doi: 10.1039/c7dt03832a
  4. Blahut Jan, Bernášek Karel, Gálisová Andrea, Herynek Ví­t, Císařová Ivana, Kotek Jan, Lang Jan, Matějková Stanislava, Hermann Petr; Paramagnetic 19F Relaxation Enhancement in Nickel(II) Complexes of N-Trifluoroethyl Cyclam Derivatives and Cell Labeling for 19F MRI; Inorganic Chemistry 56(21); 2017; 13337-13348; doi: 10.1021/acs.inorgchem.7b02119
  5. Bernasek Karel, Grocky Marian, Burian Martin, Lang Jan; Stretched Gelatin Phantom for Detection of Residual Dipolar Couplings in MR Spectra and Data Analysis of Carnosine; Journal of Spectroscopy 2016; 2016; Article ID 4596542; doi: 10.1155/2016/4596542
  6. Vesely Martin, Bultreys Tom, Peksa Mikulas, Lang Jan, Cnudde Veerle, Van Hoorebeke Luc, Kocirik Milan, Hejtmanek Vladimir, Solcova Olga, Soukup Karel, Gerke Kirill, Stallmach Frank, Capek Pavel; Prediction and Evaluation of Time-Dependent Effective Self-diffusivity of Water and Other Effective Transport Properties Associated with Reconstructed Porous Solids; Transport in Porous Media 110(1); 2015; 81-111; doi: 10.1007/s11242-015-0557-y
  7. Peksa Mikulas, Lang Jan, Stallmach Frank; C-13 NMR study of diffusion anisotropy of carbon dioxide adsorbed in nanoporous DMOF-1; MICROPOROUS AND MESOPOROUS MATERIALS 205(SI); 2015; 11-15; doi: 10.1016/j.micromeso.2014.09.039
  8. Peksa Mikuláš, Burrekaew Sareeya, Schmid Rochus, Lang Jan, Stallmach Frank; Rotational and translational dynamics of CO2 adsorbed in MOF Zn2(bdc)2(dabco); Microporous and Mesoporous Materials 216(); 2015; 75 - 81; doi: 10.1016/j.micromeso.2015.02.043
  9. Soltesova Maria, Benda Ladislav, Peksa Mikulas, Czernek Jiri, Lang Jan; Determination of Size of Molecular Clusters of Ethanol by Means of NMR Diffusometry and Hydrodynamic Calculations; JOURNAL OF PHYSICAL CHEMISTRY B 118(24); 2014; 6864-6874; doi: 10.1021/jp501648x
  10. Takacs Z., Soltesova M., Kowalewski J., Lang J., Brotin T., Dutasta J. -P.; Host-guest complexes between cryptophane-C and chloromethanes revisited; MAGNETIC RESONANCE IN CHEMISTRY 51(1); 2013; 19-31; doi: 10.1002/mrc.3898
  11. Takacs Zoltan, Brotin Thierry, Dutasta Jean-Pierre, Lang Jan, Todde Guido, Kowalewski Jozef; Inclusion of Chloromethane Guests Affects Conformation and Internal Dynamics of Cryptophane-D Host; JOURNAL OF PHYSICAL CHEMISTRY B 116(27); 2012; 7898-7913; doi: 10.1021/jp303469x
  12. Divisova Hana, Lang Jan, Rotter Milos, Schmoranzer David; MEASUREMENT OF VISCOSITY IN SMALL VOLUMES OF FLUIDS BY TUNING FORK OSCILLATORS; EFM11 - EXPERIMENTAL FLUID MECHANICS 2011 25; 2012; doi: 10.1051/epjconf/20122501008
  13. Mackova Michaela, Himl Michal, Minarova Lenka, Lang Jan, Lhotak Pavel; Regioselective deuteration of 25,27-dialkoxycalix[4]arenes; TETRAHEDRON LETTERS 52(20); 2011; 2543-2546; doi: 10.1016/j.tetlet.2011.03.030
  14. Srb Pavel, Vlach Jiri, Prchal Jan, Grocky Marian, Ruml Tomas, Lang Jan, Hrabal Richard; Oligomerization of a Retroviral Matrix Protein Is Facilitated by Backbone Flexibility on Nanosecond Time Scale; JOURNAL OF PHYSICAL CHEMISTRY B 115(11); 2011; 2634-2644; doi: 10.1021/jp110420m
  15. Herynkova Katerina, Kusova Katerina, Cibulka Ondrej, Pelant Ivan, Lang Jan; SILICON NANOCRYSTALS WITH ORGANIC PASSIVATION: MORE EFFICIENT LUMINESCENCE FROM SILICON;; 2011; 18-24;
  16. Kusova Katerina, Cibulka Ondrej, Dohnalova Katerina, Pelant , Valenta Jan, Fucikova Anna, Zidek Karel, Lang Jan Englich Jiri, Matejka Pavel, Stepanek Petr, Bakardjieva Snejana; Brightly Luminescent Organically Capped Silicon Nanocrystals Fabricated at Room Temperature and Atmospheric Pressure; ACS NANO 4(8); 2010; 4495-4504; doi: 10.1021/nn1005182
  17. Takacs Z., Soltesova M., Kotsyubynskyy D., Kowalewski J., Lang J., Brotin T., Dutasta J. P.; NMR investigation of guest-host complex between chloroform and cryptophane C; MAGNETIC RESONANCE IN CHEMISTRY 48(8); 2010; 623-629; doi: 10.1002/mrc.2637
  18. Dolensky Bohumil, Kvicala Jaroslav, Paleta Oldrich, Lang Jan, Dvorakova Hana, Cejka Jan; Trifluoromethylated (tetrahydropyrrolo) quinazolinones by a new reaction and facile assignment of the regio- and stereoisomers formed by NMR spectroscopy; MAGNETIC RESONANCE IN CHEMISTRY 48(5); 2010; 375-385; doi: 10.1002/mrc.2580
  19. Vlach Jiri, Srb Pavel, Prchal Jan, Grocky Marian, Lang Jan, Ruml Tomas, Hrabal Richard; Nonmyristoylated Matrix Protein from the Mason-Pfizer Monkey Virus Forms Oligomers; JOURNAL OF MOLECULAR BIOLOGY 390(5); 2009; 967-980; doi: 10.1016/j.jmb.2009.05.063
  20. Brauer Gerhard, Anwand Wolfgang, Grambole Dieter, Egger , Sperr Peter, Beinik Igor, Wang Lin, Teichert , Kuriplach Jan, Lang Jan, Zviagins Sergei, Erik, Ling Chi Chung, Hsu Yuk Fan, Xi Yan Yan, Chen Xinyi, Djurisic Aleksandra B., Skorupa Wolfgang; Characterization of ZnO nanostructures: A challenge to positron annihilation spectroscopy and other methods; 6(11); 2009; 2556-2560; doi: 10.1002/pssc.200982081
  21. Vlach Jiri, Lipov Jan, Rumlova Michaela, Veverka Vaclav, Jan, Srb Pavel, Knejzlik Zdenek, Pichova Iva, Hunter Eric, Hrabal Richard, Ruml Tomas; D-retrovirus morphogenetic switch driven by the targeting signal accessibility to Tctex-1 of dynein; PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 105(30); 2008; 10565-10570; doi: 10.1073/pnas.0801765105
  22. Lang Jan, Dybal Jiri, Makrlik Emanuel, Vanura Petr, Vasickova Sona, Malon Petr; Extraction and DFT study on the complexation of H3O+ with hexaethyl p-tert-butylcalix[6]arene hexaacetate; JOURNAL OF MOLECULAR STRUCTURE 846(1-3); 2007; 157-160; doi: 10.1016/j.molstrue.2007.01.037
  23. Dvorakova Hana, Lang Jan, Vlach Jiri, Sykora Jan, Cajan , Himl Michal, Pojarova Michaela, Stibor Ivan, Lhotak Pavel; Partially O-Alkylated thiacalix[4]arenes: Synthesis, molecular and crystal structures, conformational behavior; JOURNAL OF ORGANIC CHEMISTRY 72(19); 2007; 7157-7166; doi: 10.1021/jo070927i
  24. Kriz Jaroslav, Dybal Jiri, Makrlik Emanuel, Vanura Petr, Lang Jan; A proton complex of p-tert-butylcalix[4]arene-tetrakis (N,N-dimethylthioacetamide): NMR evidence and probable structure; SUPRAMOLECULAR CHEMISTRY 19(6); 2007; 419-424; doi: 10.1080/10610270601089360
  25. Dybal J., Makrlik E., Vanura P., Lang J.; A combined experimental and theoretical study on the complexation of H3O+ with hexaethyl calix[6]arene hexaacetate; ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY \& CHEMICAL PHYSICS 221(4); 2007; 519-525; doi: 10.1524/zpch.2007.221.4.519
  26. Lang J, Vagnerova K, Czernek J, Lhotak P; Flip-flop motion of circular hydrogen bond array in thiacalix[4]arene; SUPRAMOLECULAR CHEMISTRY 18(4); 2006; 371-381; doi: 10.1080/10610270600650790
  27. Lang J, Deckerova V, Czernek J, Lhotak P; Dynamics of circular hydrogen bond array in calix[4]arene in a nonpolar solvent: A nuclear magnetic resonance study; JOURNAL OF CHEMICAL PHYSICS 122(4); 2005; doi: 10.1063/1.1814971
  28. Veverka V, Bauerova H, Zabransky A, Lang J, Ruml T, Pichova I, Hrabal R; Three-dimensional structure of a monomeric form of a retroviral protease; JOURNAL OF MOLECULAR BIOLOGY 333(4); 2003; 771-780; doi: 10.1016/j.jmb.2003.08.049
  29. Lang J, Tosner Z, Lhotak P, Kowalewski J; Reorientational dynamics of two isomers of thiacalix[4]arene; MAGNETIC RESONANCE IN CHEMISTRY 41(10); 2003; 819-827; doi: 10.1002/mrc.1273
  30. Lhotak P, Himl M, Stibor I, Sykora J, Dvorakova H, Lang J, Petrickova H; Conformational behaviour of tetramethoxythiacalix[4]arenes: solution versus solid-state study; TETRAHEDRON 59(38); 2003; 7581-7585; doi: 10.1016/S0040-4020(03)01171-2
  31. Tosner Z, Lang J, Sandstrom D, Petrov O, Kowalewski J; Dynamics of an inclusion complex of dichloromethane and cryptophane-E; JOURNAL OF PHYSICAL CHEMISTRY A 106(38); 2002; 8870-8875; doi: 10.1021/jp026066t
  32. Cajan M, Lhotak P, Lang J, Dvorakova H, Stibor I, Koca J; The conformational behaviour of thiacalix[4]arenes: the pinched cone-pinched cone transition; JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2(11); 2002; 1922-1929; doi: 10.1039/b204955d
  33. Lang J, Dechter JJ, Effemey M, Kowalewski J; Dynamics of an inclusion complex of chloroform and cryptophane-E: Evidence for a strongly anisotropic van der Waals bond; JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 123(32); 2001; 7852-7858; doi: 10.1021/ja004349y
  34. Lang J, Vlach J, Dvorakova H, Lhotak P, Himl M, Hrabal R, Stibor I; Thermal isomerisation of isolation of all four conformers; JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2(4); 2001; 576-580; doi: 10.1039/b007887p
  35. Effemey M, Lang J, Kowalewski J; Multiple-field carbon-13 and proton relaxation in sucrose in viscous solution; MAGNETIC RESONANCE IN CHEMISTRY 38(12); 2000; 1012-1018; doi: 10.1002/1097-458X(200012)38:12<1012::AID-MRC785>3.0.CO;2-O
  36. Lhotak P, Kaplanek L, Stibor I, Lang J, Dvorakova H, Hrabal R, Sykora J; NMR and X-ray analysis of 25,27-dimethoxythiacalix[4] arene: unique infinite channels in the solid state; TETRAHEDRON LETTERS 41(48); 2000; 9339-9344; doi: 10.1016/S0040-4039(00)01696-8
  37. Czernek J, Lang J, Sklenar V; Ab initio calculations of spin-spin coupling constants in anhydrodeoxythymidines; JOURNAL OF PHYSICAL CHEMISTRY A 104(12); 2000; 2788-2792; doi: 10.1021/jp9937050
  38. Lang J, Chmelova K, Stepanek J, Kowalewski J, Holy A; Applicability of spectroscopic methods in the investigation of metal cation binding to adenine mononucleotides and their analogues; JOURNAL OF MOLECULAR STRUCTURE 481(SI); 1999; 363-367;
  39. Lang J, Dvorakova H, Bartosova I, Lhotak P, Stibor I, Hrabal R; Conformational flexibility of a novel tetraethylether of A comparison with the classical methylene-bridged compounds; TETRAHEDRON LETTERS 40(2); 1999; 373-376; doi: 10.1016/S0040-4039(98)02315-6
  40. Stepanek J, Kowalewski J, Lang J, Mojzes P; Spectroscopic investigation of nickel cation binding with adenine stability and structure of the 1 : 2 complex with adenosine 5 -monophosphate; JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY 3(5); 1998; 543-556; doi: 10.1007/s007750050266
  41. MALER L, LANG J, WIDMALM G, KOWALEWSKI J; MULTIPLE-FIELD C-13 NMR RELAXATION INVESTIGATION ON MELEZITOSE; MAGNETIC RESONANCE IN CHEMISTRY 33(7); 1995; 541-548; doi: 10.1002/mrc.1260330708